In this article, we will explore the benefits and practical design recommendations for using the ADUM1250ARZ-RL7 in I2C isolated communication. As industrial systems become increasingly interconnected, the need for reliable, noise-resistant, and fault-tolerant communication systems grows. The ADUM1250ARZ-RL7, a highly effective digital isolator from Analog Devices, offers a solution for these challenges. By examining its applications and design considerations, we will provide readers with an in-depth understanding of how to integrate this device into I2C-based systems effectively.